Fmoc-Thr[GalNAc(Ac)3-α-D]-OH
CAS No. 116783-35-8
Fmoc-Thr[GalNAc(Ac)3-α-D]-OH ( Fmoc-Thr(Ac?AcNH-α-Gal)-OH )
Catalog No. M29865 CAS No. 116783-35-8
AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 60 | Get Quote |
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5MG | 98 | Get Quote |
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10MG | 147 | Get Quote |
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25MG | 246 | Get Quote |
|
50MG | 425 | Get Quote |
|
100MG | 608 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
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Biological Information
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Product NameFmoc-Thr[GalNAc(Ac)3-α-D]-OH
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NoteResearch use only, not for human use.
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Brief DescriptionAZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.
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DescriptionAZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.(In Vitro):The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA, making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a majority of human carcinomas of all types, arises from a blockage in the normal O-glycosylation pathway in which glycans are extended from the common precursor GalNAcα1-O-Ser/Thr (Tn +antigen). This precursor is generated in the Golgi apparatus on newly synthesized glycoproteins by a family of polypeptide α- N-acetylgalactosaminyltransferases (ppGalNAcTs) and then extended to the common core 1 O-glycan Galβ1-3GalNAcα1-OSer/Thr (T antigen) by a single enzyme termed the T-synthase (core 1 β3-galactosyltransferase or C1GalT). Formation of the active form of the T-synthase requires a unique molecular chaperone termed Cosmc, encoded by Cosmc on the X-chromosome.
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SynonymsFmoc-Thr(Ac?AcNH-α-Gal)-OH
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number116783-35-8
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Formula Weight670.7
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Molecular FormulaC33H38N2O13
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Ju T, et al. The Cosmc connection to the Tn antigen in cancer. Cancer Biomark. 2014 Jan 1;14(1):63-81.
molnova catalog
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